SENP2 polyclonal antibody
产品名称： SENP2 polyclonal antibody
英文名称： SENP2 polyclonal antibody
产品编号： PAB2414
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of SENP2.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human SENP2.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya KNat Genet. 2004 Jan;36(1):40-5. Epub 2003 Dec 21.
- 2.
- Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex.
Zhang H, Saitoh H, Matunis MJ.Mol Cell Biol. 2002 Sep;22(18):6498-508.
- 3.
- Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T.DNA Res. 2002 Jun 30;9(3):99-106.
- Applications
- Western Blot (Tissue lysate)
- The SENP2 polyclonal antibody (Cat # PAB2414) is used in Western blot to detect SENP2 in mouse heart tissue lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with the SENP2 polyclonal antibody (Cat # PAB2414) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Entrez GeneID:
- 59343
- Protein Accession#:
- NP_067640;Q9HC62
- Gene Name:
- SENP2
- Gene Alias:
- AXAM2,DKFZp762A2316,KIAA1331,SMT3IP2
- Gene Description:
- SUMO1/sentrin/SMT3 specific peptidase 2
- Omim ID:
- 608261
- Gene Ontology:
- Hyperlink
- Gene Summary:
- SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM
- Other Designations:
- SUMO1/sentrin/SMT3 specific protease 2,sentrin-specific protease
- Gene Pathway