HOXB8 polyclonal antibody
产品名称： HOXB8 polyclonal antibody
英文名称： HOXB8 polyclonal antibody
产品编号： PAB14654
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of HOXB8.
- Immunogen:
- A synthetic peptide corresponding to amino acids 110-125 of human HOXB8.
- Sequence:
- CKLAAASGLGEEAEGS
- Host:
- Rabbit
- Reactivity:
- Bovine, Chicken, Dog, Human, Mouse, Rat
- Specificity:
- The amino acid sequence used as immunogen is 100% homologous in human, mouse, rat, dog and bovine, and 84% in chicken.
- Form:
- Liquid
- Storage Buffer:
- In serum (50% glycerol, 0.025% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:100-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Hoxb8 is required for normal grooming behavior in mice.
Greer JM, Capecchi MR.Neuron. 2002 Jan 3;33(1):23-34.
- 2.
- HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation.
Knoepfler PS, Sykes DB, Pasillas M, Kamps MP.Oncogene. 2001 Sep 6;20(39):5440-8.
- 3.
- Inhibition of myeloid differentiation by Hoxa9, Hoxb8, and Meis homeobox genes.
Fujino T, Yamazaki Y, Largaespada DA, Jenkins NA, Copeland NG, Hirokawa K, Nakamura T.Exp Hematol. 2001 Jul;29(7):856-63.
- Application Image
- ELISA
- Entrez GeneID:
- 3218
- Protein Accession#:
- NP_076921
- Gene Name:
- HOXB8
- Gene Alias:
- HOX2,HOX2D,Hox-2.4
- Gene Description:
- homeobox B8
- Omim ID:
- 142963
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania. [provided by RefSeq
- Other Designations:
- homeo box 2D,homeo box B8