UBTF (Human) Recombinant Protein (Q01)
产品名称: UBTF (Human) Recombinant Protein (Q01)
英文名称: UBTF (Human) Recombinant Protein (Q01)
产品编号: H00007343-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- Specification
- Product Description:
- Human UBTF partial ORF ( NP_055048, 551 a.a. - 650 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- PPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYIS
- Theoretical MW (kDa):
- 36.74
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Publication Reference
- 1.
- Remodeling of ribosomal genes in somatic cells by Xenopus egg extract.
Ostrup O, Hyttel P, Klarke DA, Collas P.Biochem Biophys Res Commun. 2011 Aug 6. [Epub ahead of print]
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 7343
- GeneBank Accession#:
- NM_014233
- Protein Accession#:
- NP_055048
- Gene Name:
- UBTF
- Gene Alias:
- NOR-90,UBF
- Gene Description:
- upstream binding transcription factor, RNA polymerase I
- Omim ID:
- 600673
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Upstream binding factor (UBF) is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1 (a complex of TBP (MIM 600075) and multiple TBP-associated factors or 'TAFs'). Two UBF polypeptides, of 94 and 97 kD, exist in the human (Bell et al., 1988 [PubMed 3413483]). UBF is a nucleolar phosphoprotein with both DNA binding and transactivation domains. Sequence-specific DNA binding to the core and upstream control elements of the human rRNA promoter is mediated through several HMG boxes (Jantzen et al., 1990 [PubMed 2330041]).[supplied by OMIM
- Other Designations:
- -