NAT1 (Human) Recombinant Protein (P01)
产品名称： NAT1 (Human) Recombinant Protein (P01)
英文名称： NAT1 (Human) Recombinant Protein (P01)
产品编号： H00000009-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
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- Specification
- Product Description:
- Human NAT1 full-length ORF ( NP_000653.3, 1 a.a. - 290 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVRRNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIVDAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDLLEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLTHRRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQRKLVPKHGDRFFTI
- Theoretical MW (kDa):
- 60.3
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Publication Reference
- 1.
- Elucidation of xenobiotic metabolism pathways in human skin and human skin models by proteomic profiling.
van Eijl S, Zhu Z, Cupitt J, Gierula M, Gotz C, Fritsche E, Edwards RJ.PLoS One. 2012;7(7):e41721. Epub 2012 Jul 26.
- 2.
- Phenotype of the Most Common "Slow Acetylator" Arylamine N-Acetyltransferase 1 Genetic Variant (NAT1*14B) is Substrate-Dependent.
Millner LM, Doll MA, Cai J, States JC, Hein DW.Drug Metab Dispos. 2011 Oct 18.
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 9
- GeneBank Accession#:
- NM_000662.4
- Protein Accession#:
- NP_000653.3
- Gene Name:
- NAT1
- Gene Alias:
- AAC1,NATI
- Gene Description:
- N-acetyltransferase 1 (arylamine N-acetyltransferase)
- Omim ID:
- 108345
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human geneome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- N-acetyltransferase 1,OTTHUMP00000122488,arylamide acetylase 1 (N-acetyltransferase 1),arylamine N-acetyltransferase 1
- Related Disease
- Abnormalities, Drug-Induced
- Adenocarcinoma
- Adenoma
- Alcoholism
- Alzheimer Disease
- Alzheimer disease
- Amnesia
- Asthma
- Asthma
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma, Hepatocellular
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Pancreatic Ductal
- Carcinoma, Small Cell
- Carcinoma, Squamous Cell
- Carcinoma, Transitional Cell
- Cardiovascular Diseases