RPS6KA1 monoclonal antibody, clone 8C12
产品名称： RPS6KA1 monoclonal antibody, clone 8C12
英文名称： RPS6KA1 monoclonal antibody, clone 8C12
产品编号： MAB0792
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant RPS6KA1.
- Immunogen:
- Recombinant His fusion protein corresponding to amino acids 418-735 of human RPS6KA1.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Concentration:
- 1 mg/mL
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:1800)
Immunoprecipitation (0.5 ul)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity.
Roux PP, Richards SA, Blenis J.Mol Cell Biol. 2003 Jul;23(14):4796-804.
- 2.
- Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction.
Frodin M, Gammeltoft S.Mol Cell Endocrinol. 1999 May 25;151(1-2):65-77.
- 3.
- Evidence for two catalytically active kinase domains in pp90rsk.
Fisher TL, Blenis J.Mol Cell Biol. 1996 Mar;16(3):1212-9.
- Entrez GeneID:
- 6195
- Gene Name:
- RPS6KA1
- Gene Alias:
- HU-1,MAPKAPK1A,RSK,RSK1
- Gene Description:
- ribosomal protein S6 kinase, 90kDa, polypeptide 1
- Omim ID:
- 601684
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
- Other Designations:
- OTTHUMP00000004113,S6K-alpha 1,dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1),p90-RSK 1,ribosomal protein S6 kinase alpha 1,ribosomal protein S6 kinase, 90kD, 1,ribosomal protein S6 kinase, 90kD, polypeptide 1